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          當前位置:首頁技術文章VASP抗原,血管擴張刺激磷蛋白抗原

          VASP抗原,血管擴張刺激磷蛋白抗原

          更新時間:2024-12-11點擊次數:165


          Recombinant human VASP   

          Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

          濃度:1mg/ ml

          來源:Recombinant Human

          純度:≥95% SDS-PAGE

          表達系統:Escherichia coli

          標簽:His tag  

          蛋白長度:Full length protein

          內毒素水平:<1.000 Eu/µg

          純化方法:HPLC

          應用:SDS-PAGE,Western blot,ELISA

          Biological activity,immunology research

          保存:-20℃

          保質期:1年

          Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.




          產品名稱:Rabbit Anti-VASP  antibody

          Rabbit Anti-VASP  

          別名:Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

          來源:Rabbit

          克隆類型:Polyclonal

          濃度:1mg/ml

          亞型:IgG

          應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          反應:Human,Mouse,Rat (predicted: Cow,Dog)

          理論分子量:40kDa

          免疫原:KLH conjugated synthetic peptide derived from human VASP

          保存:-20
          保質期:1

           

          單克隆抗體

          產品名稱:Anti-VASP antibody

          Mouse Anti-VASP 

          別名:Vasodilator stimulated phosphoprotein; Vasodilator-stimulated phosphoprotein; VASP; VASP_HUMAN. 

          來源:Mouse

          克隆類型:Monoclonal

          濃度:1mg/ml

          亞型:IgG

          應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          反應: Human

          理論分子量:40kDa

          免疫原:KLH conjugated synthetic peptide derived from human VASP

          保存:-20
          保質期:1

          Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

           

           


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