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          當前位置:首頁技術文章VAV1抗原,鳥苷酸轉換因子VAV1抗原

          VAV1抗原,鳥苷酸轉換因子VAV1抗原

          更新時間:2024-12-04點擊次數:173

          Recombinant human VAV1   

          Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

          濃度:1mg/ ml

          來源:Recombinant Human

          純度:≥95% SDS-PAGE

          表達系統:Escherichia coli

          標簽:His tag N-Terminus

          蛋白長度:Full length protein

          內毒素水平:<1.000 Eu/µg

          純化方法:HPLC

          應用:SDS-PAGE,Western blot,ELISA

          Biological activity,immunology research

          保存:-20℃

          保質期:1年

          This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 



          產品名稱:Rabbit Anti-VAV1  antibody

          Rabbit Anti-VAV1  

          別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .     

          來源:Rabbit

          克隆類型:Polyclonal

          濃度:1mg/ml

          亞型:IgG

          應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          反應:Human (predicted: Mouse,Rat,Pig,Cow,Horse)

          理論分子量:98kDa

          免疫原:KLH conjugated synthetic peptide derived from human VAV1

          保存:-20
          保質期:1

           

          單克隆抗體

          產品名稱:Anti-VAV1 antibody

          Mouse Anti-VAV1 

          別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

          來源:Mouse

          克隆類型:Monoclonal

          濃度:1mg/ml

          亞型:IgG

          應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

          反應: Human

          理論分子量:98kDa

          免疫原:KLH conjugated synthetic peptide derived from human VAV1

          保存:-20
          保質期:1

          This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 


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